Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | LCAT | P04180 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578382 | 0.81 | MAPT (0.48) | ADRB1SMN1; SMN2ALDH1A1KDM4EAPAF1 | |
| Hydrochloric Acid SCHEMBL1962520 | 0.80 | MAPT (0.47) | ADRB1SMN1; SMN2ALDH1A1KDM4EAPAF1 | |
| SCHEMBL6767507 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KDM4EMAPTPIM1 | |
| SCHEMBL9199798 | 0.76 | SLC6A2 (0.36) | PARP1ALDH1A1KDM4EPIM1SLC6A2 | |
| SCHEMBL3068463 | 0.75 | ADRB1 (0.42) | ADRB1SCN9AALDH1A1MAPTLCAT | |
| SCHEMBL8195822 | 0.75 | SLC6A2 (0.46) | ADRB1SCN9AALDH1A1MAPTSLC6A2 | |
| SCHEMBL28817805 | 0.75 | ADRB1 (0.56) | ADRB1SCN9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3081103 | 0.74 | ADRB1 (0.62) | ADRB1ALDH1A1MAPTPIM1ADRB2 | |
| SCHEMBL3922344 | 0.74 | ALDH1A1 (0.53) | ADRB1PARP1SMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL21522534 | 0.72 | ALDH1A1 (0.56) | ADRB1SMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377665-A | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |