Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914143 | 1.00 | CA2 (0.48) | CA2CHKATLR8KMOCDC7 | |
| SCHEMBL30282551 | 0.71 | KMO (0.36) | KMO | |
| SCHEMBL28964988 | 0.71 | KMO (0.36) | KMO | |
| SCHEMBL9373747 | 0.69 | TLR8 (0.48) | TLR8CDC7DBF4CYP17A1GAA | |
| SCHEMBL1661899 | 0.68 | KMO (0.46) | KMOCDC7CYP17A1MAP4K4MEN1 | |
| SCHEMBL6119719 | 0.68 | KMO (0.42) | CA2CHKAKMOCDC7DBF4 | |
| SCHEMBL8167996 | 0.68 | KMO (0.46) | KMOCYP17A1KDM4EL3MBTL1 | |
| SCHEMBL15446373 | 0.68 | KMO (0.42) | KMOCYP17A1L3MBTL1 | |
| SCHEMBL29878478 | 0.68 | KMO (0.46) | KMOCYP17A1KDM4EL3MBTL1 | |
| SCHEMBL8817437 | 0.68 | KMO (0.42) | KMOCYP17A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355532-A | Tri-fused ring USP1 inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |