Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631296 | 0.83 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16291348 | 0.83 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL29427144 | 0.83 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL21117319 | 0.82 | LPL (0.38) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL30345372 | 0.82 | CA1 (0.37) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1494491 | 0.82 | CA1 (0.37) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16532525 | 0.82 | LPL (0.35) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL4242311 | 0.81 | SNCA (0.39) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL28937486 | 0.79 | LPL (0.35) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL19886494 | 0.79 | NOTUM (0.37) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114096533-B | Tri-ring compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-03-08 | — | — | CN | disclosed |