Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416937 | 0.82 | LPL (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16291348 | 0.80 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL26631296 | 0.80 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL29427144 | 0.80 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL30345372 | 0.79 | CA1 (0.37) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1494491 | 0.79 | CA1 (0.37) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16532525 | 0.79 | LPL (0.35) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL29170643 | 0.79 | LPL (0.35) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL251859 | 0.77 | LIPG (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL28433868 | 0.76 | LPL (0.38) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | disclosed |