Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.58 |
| ▸ | CTSL | P07711 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29173014 | 0.89 | MEN1 (0.54) | CTSSCTSLCTSKKMT2AMEN1 | |
| SCHEMBL11077650 | 0.89 | EGFR (0.55) | CTSSCTSLCTSKKMT2AMEN1 | |
| SCHEMBL29172972 | 0.84 | HPGD (0.64) | KMT2AMEN1L3MBTL1HDAC1HDAC6 | |
| SCHEMBL5190596 | 0.84 | CTSS (0.59) | CTSSCTSLCTSKKMT2AMEN1 | |
| SCHEMBL1003508 | 0.83 | HDAC1 (0.71) | CTSSCTSLKMT2AMEN1L3MBTL1 | |
| SCHEMBL28497560 | 0.81 | HDAC1 (0.54) | KMT2AMEN1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL1004019 | 0.80 | HDAC1 (0.71) | KMT2AMEN1L3MBTL1HDAC1HDAC6 | |
| SCHEMBL9473823 | 0.80 | EGFR (0.46) | CTSSCTSLCTSKKMT2AMEN1 | |
| Oxalic Acid SCHEMBL29264737 | 0.80 | HDAC1 (0.67) | CTSSCTSLKMT2AMEN1L3MBTL1 | |
| Oxalic Acid SCHEMBL29264739 | 0.80 | HDAC1 (0.67) | CTSSCTSLKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031553-B | Preparation method of 4- [ (methoxyacyl) methyl ] -3, 4-dihydro-isoquinoline-1 (2H) -ketone compound | 郑州师范学院 | 2024-03-22 | — | — | CN | claimed |
| CN-114031553-A | Preparation method of 4- [ (methoxyacyl) methyl ] -3, 4-dihydroisoquinoline-1 (2H) -ketone compound | 郑州师范学院 | 2022-02-11 | — | — | CN | claimed |
| CN-114031553-B | Preparation method of 4- [ (methoxyacyl) methyl ] -3, 4-dihydro-isoquinoline-1 (2H) -ketone compound | 郑州师范学院 | 2024-03-22 | — | — | CN | disclosed |
| CN-114031553-A | Preparation method of 4- [ (methoxyacyl) methyl ] -3, 4-dihydroisoquinoline-1 (2H) -ketone compound | 郑州师范学院 | 2022-02-11 | — | — | CN | disclosed |