Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172972 | 0.91 | HPGD (0.64) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL29173000 | 0.89 | CTSS (0.58) | EGFRALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL28497560 | 0.88 | HDAC1 (0.54) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL11076517 | 0.86 | HPGD (0.51) | EGFRALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL9473823 | 0.86 | EGFR (0.46) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL7573934 | 0.86 | HPGD (0.56) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL28364943 | 0.85 | EGFR (0.56) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL4182248 | 0.84 | CASR (0.43) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL11188824 | 0.83 | AKR1C3 (0.50) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL28498818 | 0.82 | ADRA2C (0.53) | EGFRALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438151-A | ADDITION COPOLYMERIZATION ON SURFACE | TEIJIN LIMITED (JP) | 1984-03-20 | — | — | US | claimed |
| US-4438151-A | ADDITION COPOLYMERIZATION ON SURFACE | TEIJIN LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| US-4407848-A | PROTECTIVE COATING OF COPOLYMER OF DIALLYL PHTHALATE AND POLYOXYETHYLENE GLYCOL ACRYLIC ESTER | TEIJIN LIMITED (JP) | 1983-10-04 | — | — | US | disclosed |