Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27526965 | 0.84 | POLB (0.49) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL29177428 | 0.84 | KMT2A (0.40) | MAPTPOLBPKMALDH1A1GLA | |
| SCHEMBL29163724 | 0.79 | MAPT (0.60) | LMNAMAPTPKMALDH1A1HSD17B10 | |
| SCHEMBL14062418 | 0.78 | MAPT (0.59) | LMNAMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL29123252 | 0.77 | SMN1; SMN2 (0.57) | LMNAMAPTPOLBALDH1A1CYP2C9 | |
| SCHEMBL3787327 | 0.76 | SMN1; SMN2 (0.60) | LMNAMAPTALDH1A1TSHRKMT2A | |
| SCHEMBL11790413 | 0.76 | KMT2A (0.57) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL28452003 | 0.76 | SMN1; SMN2 (0.63) | LMNAMAPTPOLBALDH1A1HSD17B10 | |
| SCHEMBL27337562 | 0.76 | ALDH1A1 (0.50) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL10220768 | 0.75 | CA12 (0.42) | LMNAMAPTPOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| CN-116507332-A | Octahydroisoquinolinyl derivatives | UCB生物制药有限责任公司 | 2023-07-28 | — | — | CN | disclosed |