Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LIPE | Q05469 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123252 | 0.96 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL29123592 | 0.86 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1POLBMEN1 | |
| SCHEMBL28371857 | 0.86 | RAB9A (0.47) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL19066192 | 0.80 | ALDH1A1 (0.67) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL29072025 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL22322354 | 0.76 | ALDH1A1 (0.61) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL29174281 | 0.76 | LMNA (0.50) | SMN1; SMN2MAPTALDH1A1POLBMEN1 | |
| SCHEMBL12994617 | 0.76 | ALDH1A1 (0.82) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL22601583 | 0.75 | GRM5 (0.56) | SMN1; SMN2MAPTHTTALDH1A1POLB | |
| SCHEMBL17207186 | 0.75 | GRM5 (0.56) | SMN1; SMN2MAPTHTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-111699185-B | 6-azaindole compounds | 百时美施贵宝公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-111819176-A | 4-azaindole compounds | 百时美施贵宝公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111699185-A | 6-azaindole compounds | 百时美施贵宝公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-111620864-A | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111620865-A | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |