Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 11/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30725513 | 1.00 | LRRK2 (0.40) | LRRK2CNR2CNR1CDK2SYK | |
| SCHEMBL25019280 | 0.88 | LRRK2 (0.36) | LRRK2CNR2CNR1 | |
| SCHEMBL17196815 | 0.85 | CACNA1G (0.35) | LRRK2SYK | |
| SCHEMBL26980843 | 0.84 | LRRK2 (0.43) | LRRK2CNR2CNR1 | |
| SCHEMBL19510913 | 0.83 | LRRK2 (0.48) | LRRK2 | |
| SCHEMBL25677309 | 0.82 | LRRK2 (0.42) | LRRK2CNR2CNR1 | |
| SCHEMBL5723291 | 0.80 | PIN1 (0.52) | LRRK2CNR2CNR1CDK2 | |
| SCHEMBL27082410 | 0.77 | LRRK2 (0.37) | LRRK2CDK2 | |
| SCHEMBL17196754 | 0.77 | PDCD1 (0.41) | LRRK2CNR2SYK | |
| SCHEMBL17196817 | 0.77 | ABL1 (0.40) | LRRK2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |