Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.61 |
| ▸ | CCNK | O75909 | 14/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 14/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.43 |
| ▸ | CDK9 | P50750 | 12/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.43 |
| ▸ | CDK2 | P24941 | 11/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 9/20 | 0.33 |
| ▸ | CCNH | P51946 | 8/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30725493 | 1.00 | RPS6KA5 (0.61) | RPS6KA5CCNKCDK12CCNT1CDK9 | |
| SCHEMBL31006792 | 0.80 | RPS6KA5 (0.65) | RPS6KA5CCNKCDK12CCNT1CDK9 | |
| SCHEMBL31006823 | 0.77 | CCNK (0.68) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL31006772 | 0.76 | RPS6KA5 (1.00) | RPS6KA5CCNKCDK12CCNT1CDK9 | |
| SCHEMBL17490465 | 0.76 | RPS6KA5 (1.00) | RPS6KA5CCNKCDK12CCNT1CDK9 | |
| SCHEMBL771611 | 0.71 | CAMKK2 (0.55) | CDK2CAMKK2LRRK2 | |
| SCHEMBL30554764 | 0.70 | RPS6KA5 (0.56) | RPS6KA5CCNKCDK12CCNT1CDK9 | |
| SCHEMBL21629016 | 0.70 | RPS6KA5 (0.56) | RPS6KA5CCNKCDK12CCNT1CDK9 | |
| SCHEMBL24588136 | 0.70 | CCNK (0.59) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL517461 | 0.70 | RPS6KA5 (0.66) | RPS6KA5CCNKCDK12CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |