Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 4/20 | 0.78 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.78 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.78 |
| ▸ | PDE2A | O00408 | 3/20 | 0.78 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.60 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.60 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.56 |
| ▸ | PDE5A | O76074 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10855561 | 0.90 | PDE2A (0.73) | PDE1APDE1BPDE1CPDE2ASIRT1 | |
| SCHEMBL4623475 | 0.89 | PDE1A (0.71) | PDE1APDE1BPDE1CPDE2ASIRT1 | |
| SCHEMBL897036 | 0.88 | PDE1A (1.00) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL10857602 | 0.88 | PDE1A (0.66) | PDE1APDE1BPDE1CPDE2ASIRT1 | |
| SCHEMBL9430688 | 0.87 | PDE1A (0.68) | PDE1APDE1BPDE1CPDE2ASIRT1 | |
| SCHEMBL1462083 | 0.86 | PDE1A (0.68) | PDE1APDE1BPDE1CPDE2ASIRT1 | |
| SCHEMBL9430349 | 0.86 | PDE1A (0.67) | PDE1APDE1BPDE1CPDE2ASIRT1 | |
| SCHEMBL9430566 | 0.80 | PDE2A (0.56) | PDE1APDE1BPDE1CPDE2ASIRT1 | |
| SCHEMBL1460835 | 0.80 | PDE1A (0.75) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL11286152 | 0.79 | PDE2A (0.59) | PDE1APDE1BPDE1CPDE2ASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471903-B1 | Placental stem cell populations | ANTHROGENESIS CORP (US) | 2018-02-14 | — | — | EP | claimed |
| EP-0407651-A2 | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent | J. URIACH & CIA. S.A. (ES) | 1991-01-16 | — | — | EP | claimed |
| EP-0039780-A1 | Di- or trisubstituted xanthines with neuroleptic activity, process for their preparation and pharmaceutical preparations containing them | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1981-11-18 | — | — | EP | claimed |
| EP-3174972-A1 | METHOD FOR IN VITRO PRODUCTION OF ADIPOCYTE PROGENITORS AND ADIPOCYTES | Université Pierre et Marie Curie (Paris 6) (FR) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016572-A1 | METHOD FOR IN VITRO PRODUCTION OF ADIPOCYTE PROGENITORS AND ADIPOCYTES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2016-02-04 | — | — | WO | disclosed |
| EP-2264171-A1 | Anti-myosine Va siRNA and skin depigmentation | Pierre Fabre Dermo-Cosmétique (FR) | 2010-12-22 | — | — | EP | disclosed |
| EP-1963507-B1 | ANTI-MYOSIN VA SIRNA AND SKIN DEPIGMENTATION | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-10-13 | — | — | EP | disclosed |
| WO-2010041863-A3 | MEDIA COMPOSITION FOR ADIPOCYTE DIFFERENTIATION | 숙명여자대학교산학협력단 (KR) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010041863-A8 | MEDIA COMPOSITION FOR ADIPOCYTE DIFFERENTIATION | 숙명여자대학교산학협력단 (KR) | 2010-07-29 | — | — | WO | disclosed |
| WO-2010041863-A9 | MEDIA COMPOSITION FOR ADIPOCYTE DIFFERENTIATION | 숙명여자대학교산학협력단 (KR) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010041863-A2 | MEDIA COMPOSITION FOR ADIPOCYTE DIFFERENTIATION | 숙명여자대학교산학협력단 (KR) | 2010-04-15 | — | — | WO | disclosed |
| EP-0618801-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING A BLACK HOREHOUND EXTRACT | LVMH RECHERCHE (FR) | 1994-10-12 | — | — | EP | disclosed |
| EP-0591027-A1 | Piperidine derivatives, their preparation and their use as medicine | SYNTHELABO (FR) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993010804-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING A BLACK HOREHOUND EXTRACT | LVMH RECHERCHE (FR) | 1993-06-10 | — | — | WO | disclosed |
| EP-0407651-A2 | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent | J. URIACH & CIA. S.A. (ES) | 1991-01-16 | — | — | EP | disclosed |
| EP-0407651-A2 | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent | J. URIACH & CIA. S.A. (ES) | 1991-01-16 | — | — | EP | disclosed |
| EP-0407651-A2 | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent | J. URIACH & CIA. S.A. (ES) | 1991-01-16 | — | — | EP | disclosed |
| US-4581451-A | ALKYLATION AND CYCLIZATION OF A URACIL COMPOUND | NESTEC S.A. (CH) | 1986-04-08 | — | — | US | disclosed |
| US-4469698-A | SEDATIVES, TRANQUILIZERS | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1984-09-04 | — | — | US | disclosed |
| EP-0039780-A1 | Di- or trisubstituted xanthines with neuroleptic activity, process for their preparation and pharmaceutical preparations containing them | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 1981-11-18 | — | — | EP | disclosed |