Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 6/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 6/20 | 1.00 |
| ▸ | PDE1C | Q14123 | 6/20 | 1.00 |
| ▸ | PDE2A | O00408 | 3/20 | 1.00 |
| ▸ | PDE5A | O76074 | 9/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | SCN1A | P35498 | 1/20 | 0.58 |
| ▸ | PDE6C | P51160 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917587 | 0.88 | PDE1A (0.78) | PDE1APDE1BPDE1CPDE2APDE5A | |
| Verofylline SCHEMBL636856 | 0.87 | PDE1A (0.78) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL1460835 | 0.86 | PDE1A (0.75) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL11607287 | 0.85 | PDE1A (0.74) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL10855561 | 0.85 | PDE2A (0.73) | PDE1APDE1BPDE1CPDE2AADORA1 | |
| SCHEMBL6869474 | 0.84 | PDE1A (0.72) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL4623475 | 0.83 | PDE1A (0.71) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL2917588 | 0.83 | PDE5A (0.74) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL25249437 | 0.82 | PDE1A (0.69) | PDE1APDE1BPDE1CPDE2APDE5A | |
| SCHEMBL9121409 | 0.82 | PDE1A (1.00) | PDE1APDE1BPDE1CPDE2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525329-A | INCREASED SENSITIVITY TO ODORS | THE JOHNS HOPKINS UNIVERSITY (US) | 1996-06-11 | — | — | US | claimed |
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | claimed |
| US-4089959-A | Long-acting xanthine bronchodilators and antiallergy agents | COOPER LABORATORIES, INC. (US) | 1978-05-16 | — | — | US | claimed |
| US-20260109783-A1 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE | MESOBLAST, INC. (US) | 2026-04-23 | — | — | US | disclosed |
| US-12275801-B2 | Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase | MESOBLAST, INC. (US) | 2025-04-15 | — | — | US | disclosed |
| US-20240101961-A1 | Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof | MESOBLAST, INC. (US) | 2024-03-28 | — | — | US | disclosed |
| US-20210355447-A1 | Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof | MESOBLAST, INC. (US) | 2021-11-18 | — | — | US | disclosed |
| US-20200332023-A1 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE | MESOBLAST, INC. (US) | 2020-10-22 | — | — | US | disclosed |
| US-10609922-B2 | Protection of progenitor cells and regulation of their differentiation | PROTEOBIOACTIVES PTY LTD (AU) | 2020-04-07 | — | — | US | disclosed |
| EP-2380971-B1 | PERIVASCULAR MESENCHYMAL PRECURSOR CELLS | MESOBLAST INC (US) | 2020-02-12 | — | — | EP | disclosed |
| WO-1997032898-A1 | ANTI-INFLAMMATORY CRF ANALOGS, THEIR COMPOSITIONS AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-12 | — | — | WO | disclosed |
| US-5648387-A | Carboxyalkylethers, formulations, and treatment of vascular diseases | WARNER-LAMBERT COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| WO-1996030328-A1 | TERMINAL CARBOXY OR TETRAZOLE GROUPS CONTAINING DIALKYL ETHERS | WARNER-LAMBERT COMPANY (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5470579-A | Xanthines, optionally incorporated in liposomes, for promoting skin or hair pigmentation | LVMH, RECHERCHE (FR) | 1995-11-28 | — | — | US | disclosed |
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | disclosed |
| US-4089959-A | Long-acting xanthine bronchodilators and antiallergy agents | COOPER LABORATORIES, INC. (US) | 1978-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10609922-B2 | Protection of progenitor cells and regulation of their differentiation | CD44, MCL1, NES | PDE1A 4165/4885PDE1B 3791/4885PDE1C 3973/4885 |
| US-20260109783-A1 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE | ALPP, S100P, ALPG | PDE1A 249/4885PDE1B 297/4885PDE1C 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.