Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727136 | 0.95 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2TSHRMAPK1PHGDH | |
| SCHEMBL11340621 | 0.87 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2TSHRMAPK1MGLL | |
| SCHEMBL2918327 | 0.83 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2TSHRMAPK1MAPT | |
| SCHEMBL21081716 | 0.83 | ALDH1A1 (0.92) | ALDH1A1SMN1; SMN2TSHRMAPK1NPC1 | |
| SCHEMBL10941442 | 0.83 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TSHRMAPK1PHGDH | |
| SCHEMBL10940747 | 0.83 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2TSHRMAPK1PHGDH | |
| SCHEMBL9291268 | 0.81 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2TSHRMAPK1PHGDH | |
| SCHEMBL27630183 | 0.81 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2TSHRMAPK1NPC1 | |
| SCHEMBL701448 | 0.81 | MAPK1 (0.70) | ALDH1A1SMN1; SMN2TSHRMAPK1NPC1 | |
| SCHEMBL2705294 | 0.80 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2TSHRMAPK1PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388538-B1 | Polymerisation Initiator | MERCK PATENT GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1388538-A1 | Polymerisation Initiator | MERCK PATENT GmbH (DE) | 2004-02-11 | — | — | EP | disclosed |
| US-6022906-A | α-aminoacetophenone photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-08 | — | — | US | disclosed |