SCHEMBL4948645

SCHEMBL4948645

NCCNCC=Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.54
RAB9A P51151 1/20 0.46
KDM4E B2RXH2 1/20 0.46
IDO1 P14902 2/20 0.46
ALDH1A1 P00352 1/20 0.44
S1PR1 P21453 3/20 0.44
S1PR3 Q99500 2/20 0.44
HTR2A P28223 3/20 0.43
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28725423 1.00 PRMT1 (0.54) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL29176161 0.91 PRMT1 (0.50) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL11032133 0.91 PRMT1 (0.50) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL30694747 0.90 PRMT1 (0.49) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL28520466 0.90 PRMT1 (0.49) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL11597357 0.88 PRMT1 (0.55) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL11597360 0.88 PRMT1 (0.55) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL2770965 0.83 KDM4E (0.55) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL2770961 0.83 KDM4E (0.55) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL3305133 0.81 HDAC3 (0.49) PRMT1RAB9AKDM4EALDH1A1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451753-A1 In the ethylenic moiety substituted phenylalkylethylenediamine-platinum (II or IV) derivatives and phenylalkyl-ethylenediamines ASTA Medica Aktiengesellschaft (DE) 1991-10-16 EP claimed
US-20260054913-A1 CONTACT LENSES HAVING CATIONIC MONOMERS OR CATIONIC POLYMERS FOR RELEASING COMFORT AGENTS CITIBANK, N.A., AS NOTES COLLATERAL AGENT 2026-02-26 US disclosed
CN-116391140-B Cationic contact lens 库博光学国际有限公司 2025-01-10 CN disclosed
CN-118251617-A Cationic contact lenses 库博光学国际有限公司 2024-06-25 CN disclosed
CN-115668002-B Contact lenses releasing oleic acid 库博光学国际有限公司 2023-09-15 CN disclosed
CN-116391140-A Cationic contact lens 库博光学国际有限公司 2023-07-04 CN disclosed
CN-116376137-A Polyethylene master batch, preparation method and antistatic polyethylene pipe 廊坊北化高分子材料有限公司 2023-07-04 CN disclosed
CN-115668002-A Oleic acid releasing contact lenses 库博光学国际有限公司 2023-01-31 CN disclosed
CN-114230950-A Semiconductor equipment sealing element and preparation method thereof 上海芯密科技有限公司 2022-03-25 CN disclosed
CN-104204294-B Promote the method for sticky limit between dielectric substrate and metal layer 德国艾托特克公司 2018-12-07 CN disclosed
CN-107112311-A Method for the electromagnetic shielding and heat management of driving component 德国艾托特克公司 2017-08-29 CN disclosed
CN-107112224-A Cabosil chemically-mechanicapolish polishes concentrate 嘉柏微电子材料股份公司 2017-08-29 CN disclosed
US-8961831-B2 Silane-containing pigment particles for electrophoretic display E INK CALIFORNIA, LLC (US) 2015-02-24 US disclosed
US-20140339480-A1 SILANE-CONTAINING PIGMENT PARTICLES FOR ELECTROPHORETIC DISPLAY E INK CORPORATION 2014-11-20 US disclosed
WO-2008026075-A2 TREATMENT OF INTRACELLULAR BACTERIAL INFECTIONS WITH A PROTEIN KINASE INHIBITOR OR AN AS160 POLYPEPTIDE ACTIVATOR VERENIGING HET NEDERLANDS KANKER INSTITUUT (NL) 2008-03-06 WO disclosed
US-5238955-A Anticarcinogenic agents ASTA PHARMA AG (DE) 1993-08-24 US disclosed
US-5238955-A Anticarcinogenic agents ASTA PHARMA AG (DE) 1993-08-24 US disclosed
US-5194644-A Antitumor agents; treatment of leukemia ASTA PHARMA AG (DE) 1993-03-16 US disclosed
EP-0451753-A1 In the ethylenic moiety substituted phenylalkylethylenediamine-platinum (II or IV) derivatives and phenylalkyl-ethylenediamines ASTA Medica Aktiengesellschaft (DE) 1991-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260054913-A1 CONTACT LENSES HAVING CATIONIC MONOMERS OR CATIONIC POLYMERS FOR RELEASING COMFORT AGENTS TRPA1, ASIC1, ARGLU1 PRMT1 1489/4885RAB9A 2294/4885KDM4E 2339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.