Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26090166 | 0.93 | CD44 (0.35) | SMN1; SMN2CD44KDM4EALDH1A1LMNA | |
| SCHEMBL29177402 | 0.85 | MEN1 (0.36) | LMNAMEN1KMT2ARAB9A | |
| SCHEMBL29177288 | 0.84 | CD44 (0.39) | SMN1; SMN2CD44KDM4EALDH1A1LMNA | |
| SCHEMBL29177282 | 0.84 | CD44 (0.39) | SMN1; SMN2CD44KDM4EALDH1A1LMNA | |
| SCHEMBL25295762 | 0.84 | CYP1A2 (0.36) | ALDH1A1MEN1KMT2ACYP1A2CYP11B1 | |
| SCHEMBL29177199 | 0.84 | MEN1 (0.35) | LMNAMEN1KMT2ARAB9A | |
| SCHEMBL29177373 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29227718 | 0.79 | MEN1 (0.32) | LMNAMEN1KMT2ARAB9A | |
| SCHEMBL29177188 | 0.79 | LMNA (0.41) | SMN1; SMN2LMNACYP1A2RAB9A | |
| SCHEMBL28645960 | 0.79 | MEN1 (0.36) | LMNAMAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |