Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177402 | 0.85 | MEN1 (0.36) | MEN1KMT2ARAB9AARHTT | |
| SCHEMBL29177199 | 0.84 | MEN1 (0.35) | MEN1KMT2ARAB9AHTTCYP4F2 | |
| SCHEMBL28892767 | 0.81 | HTR2A (0.44) | RAB9AARTSHRHTTAPOBEC3A | |
| SCHEMBL29227718 | 0.79 | MEN1 (0.32) | MEN1KMT2ARAB9AHTTCYP4F2 | |
| SCHEMBL29177226 | 0.79 | SMN1; SMN2 (0.35) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL29177188 | 0.79 | LMNA (0.41) | RAB9AARTSHRHTTLMNA | |
| SCHEMBL29236517 | 0.79 | IDO1 (0.33) | MEN1KMT2AMAPTARDGAT1 | |
| SCHEMBL29177244 | 0.79 | IRAK4 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL29177383 | 0.77 | KIF11 (0.35) | MEN1KMT2ACYP4F2CYP4A11KIF11 | |
| SCHEMBL28384779 | 0.77 | NOTUM (0.39) | MEN1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-113264945-A | Spiro derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-08-17 | — | — | CN | disclosed |