Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177310 | 0.83 | KDM4E (0.46) | ALDH1A1SMN1; SMN2KDM4EHRH3KMT2A | |
| SCHEMBL29177190 | 0.83 | ABL1 (0.50) | ALDH1A1MAPTAOC3HPGDKDM4E | |
| SCHEMBL29947770 | 0.81 | PDE4B (0.44) | ALDH1A1MAPTPDE4BSMN1; SMN2LMNA | |
| SCHEMBL29177419 | 0.79 | CNR1 (0.41) | ALDH1A1MAPTPDE4BKDM4EKMT2A | |
| SCHEMBL29115151 | 0.76 | SMN1; SMN2 (0.60) | AOC3SMN1; SMN2HPGDKDM4EHRH3 | |
| SCHEMBL29739553 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTPDE4BSMN1; SMN2LMNA | |
| SCHEMBL29177423 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTPDE4BSMN1; SMN2LMNA | |
| SCHEMBL29739537 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL26739679 | 0.75 | MAPT (0.43) | ALDH1A1MAPTPDE4BSMN1; SMN2LMNA | |
| SCHEMBL29177403 | 0.71 | CNR2 (0.43) | MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |