Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980785 | 0.79 | KDM4E (0.62) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL6288545 | 0.71 | LMNA (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL17442783 | 0.69 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL28616292 | 0.68 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| Lithium SCHEMBL30570039 | 0.68 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL21577705 | 0.68 | KDM4E (0.61) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL909196 | 0.68 | GGPS1 (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL16156201 | 0.67 | KMT2A (0.58) | ALDH1A1SMN1; SMN2KDM4EGAARXFP1 | |
| Hydrochloric Acid SCHEMBL9121777 | 0.67 | GGPS1 (0.54) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL8661446 | 0.67 | GGPS1 (0.54) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430561-A | GPR139 receptor agonist and preparation method thereof | 浙江友宁生物医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |