Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314293 | 0.88 | SIRT6 (0.60) | MAPTALDH1A1ALOX12HTTSMN1; SMN2 | |
| SCHEMBL3670266 | 0.85 | MAPT (0.56) | MAPTALDH1A1ALOX12HTTSMN1; SMN2 | |
| SCHEMBL30032873 | 0.83 | ADRB1 (0.60) | MAPTALDH1A1ALOX12HTTSMN1; SMN2 | |
| SCHEMBL29178278 | 0.82 | SMN1; SMN2 (0.75) | MAPTALDH1A1HTTSMN1; SMN2GFER | |
| SCHEMBL15225851 | 0.81 | SMN1; SMN2 (1.00) | MAPTALDH1A1HTTSMN1; SMN2GFER | |
| SCHEMBL26706253 | 0.81 | KMT2A (0.72) | MAPTALDH1A1ALOX12HTTSMN1; SMN2 | |
| Bicarbonate SCHEMBL15226070 | 0.80 | SMN1; SMN2 (0.97) | MAPTALDH1A1HTTSMN1; SMN2GFER | |
| SCHEMBL26706251 | 0.79 | KMT2A (0.70) | MAPTALDH1A1ALOX12HTTSMN1; SMN2 | |
| SCHEMBL29178287 | 0.79 | SMN1; SMN2 (0.70) | MAPTALOX12HTTSMN1; SMN2GFER | |
| SCHEMBL3635114 | 0.78 | MAPT (0.65) | MAPTALDH1A1ALOX12HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736163-A | Phenylpiperazine derivative or pharmaceutical salt thereof, preparation method and application thereof in preparation of pain treatment drugs | 郑州大学第一附属医院 | 2024-03-22 | — | — | CN | claimed |
| CN-117736163-A | Phenylpiperazine derivative or pharmaceutical salt thereof, preparation method and application thereof in preparation of pain treatment drugs | 郑州大学第一附属医院 | 2024-03-22 | — | — | CN | disclosed |