SCHEMBL29178290

SCHEMBL29178290

O=C(NS(=O)(=O)c1ccccc1)C1CNCCN1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.43
ADRB1 P08588 2/20 0.43
HTR6 P50406 6/20 0.43
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
MMP1 P03956 1/20 0.38
MMP3 P08254 1/20 0.38
MMP7 P09237 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
ALDH1A1 P00352 2/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
HTT P42858 1/20 0.36
USP2 O75604 1/20 0.36
GBA1 P04062 1/20 0.36
ALOX15 P16050 1/20 0.36
HK1 P19367 1/20 0.36
HKDC1 Q2TB90 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27672018 0.81 SLC6A2 (0.48) ADRB1SLC6A2SLC6A4SLC6A3MMP1
SCHEMBL9396845 0.78 SLC6A2 (0.53) ADRB1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL20140971 0.78 SLC6A2 (0.53) ADRB1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL27529782 0.78 SLC6A4 (0.53) ADRB1SLC6A2SLC6A4SLC6A3ALDH1A1
Hydrochloric Acid SCHEMBL20140710 0.77 SLC6A2 (0.51) ADRB1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL21360355 0.76 SLC6A4 (0.50) ADRB1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL4238187 0.76 SLC6A4 (0.50) ADRB1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL20140984 0.76 SLC6A4 (0.50) ADRB1SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL21360310 0.75 SLC6A4 (0.47) ADRB1SLC6A2SLC6A4SLC6A3MMP1
SCHEMBL16731889 0.75 SLC6A4 (0.47) ADRB1SLC6A2SLC6A4SLC6A3MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736163-A Phenylpiperazine derivative or pharmaceutical salt thereof, preparation method and application thereof in preparation of pain treatment drugs 郑州大学第一附属医院 2024-03-22 CN disclosed