Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 7/20 | 0.52 |
| ▸ | CTSS | P25774 | 6/20 | 0.52 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139652 | 1.00 | HDAC4 (0.56) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL29980244 | 0.99 | HDAC4 (0.58) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL29178440 | 0.90 | HDAC4 (0.48) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL24814246 | 0.90 | HDAC4 (0.48) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL24815327 | 0.89 | HDAC4 (0.47) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL29178303 | 0.89 | HDAC4 (0.47) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL24812379 | 0.87 | HDAC4 (0.46) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL29178310 | 0.87 | HDAC4 (0.46) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL31407339 | 0.86 | CTSK (0.54) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL18762608 | 0.86 | HDAC4 (0.52) | HDAC4HDAC1HDAC6CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |