Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 6/20 | 0.54 |
| ▸ | CTSS | P25774 | 5/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178296 | 0.99 | HDAC4 (0.56) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL25139652 | 0.99 | HDAC4 (0.56) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL29178440 | 0.89 | HDAC4 (0.48) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL24814246 | 0.89 | HDAC4 (0.48) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL24815327 | 0.88 | HDAC4 (0.47) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL29178303 | 0.88 | HDAC4 (0.47) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL31407534 | 0.87 | CTSK (0.56) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL24812379 | 0.85 | HDAC4 (0.46) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL29178310 | 0.85 | HDAC4 (0.46) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL18762608 | 0.85 | HDAC4 (0.52) | HDAC4HDAC1HDAC6CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12065445-B2 | CDK2 inhibitors and methods of using the same | CEDILLA THERAPEUTICS, INC. (US) | 2024-08-20 | — | — | US | disclosed |
| US-20240174680-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| EP-4284365-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20230109076-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. | 2023-04-06 | — | — | US | disclosed |
| WO-2022165513-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174680-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CDK2, CDK20, CDK2AP2 | HDAC4 835/4885HDAC1 448/4885HDAC6 1046/4885 |
| US-20230109076-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CDK2, CDK20, CDK2AP2 | HDAC4 835/4885HDAC1 448/4885HDAC6 1046/4885 |
| US-12065445-B2 | CDK2 inhibitors and methods of using the same | CDK2, CDK20, CDK1 | HDAC4 485/4885HDAC1 174/4885HDAC6 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.