Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24049431 | 0.86 | PSMB5 (0.53) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL26277317 | 0.85 | CTSK (0.49) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL28854958 | 0.85 | CTSK (0.49) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL12018372 | 0.81 | CACNA1B (0.44) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL27266541 | 0.80 | CTSK (0.45) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL30345605 | 0.78 | CTSK (0.44) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL24814256 | 0.78 | CTSK (0.48) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL10678122 | 0.78 | TSHR (0.39) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL24814531 | 0.78 | CTSK (0.48) | CTSKCTSSCACNA1BCTSLCTSB | |
| SCHEMBL15564433 | 0.78 | TSHR (0.39) | CTSKCTSSCACNA1BCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |