Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564433 | 1.00 | TSHR (0.39) | TSHRCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL647903 | 0.81 | AAK1 (0.41) | TSHRCTSKCTSSHDAC4HDAC1 | |
| SCHEMBL12018372 | 0.80 | CACNA1B (0.44) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL11096635 | 0.80 | CTSK (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL29178367 | 0.78 | CTSK (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL7296839 | 0.78 | CTSK (0.58) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL3709454 | 0.78 | CTSK (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL9099322 | 0.78 | CTSK (0.55) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL9062172 | 0.76 | CTSK (0.53) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL17497589 | 0.76 | CTSK (0.42) | CTSKCTSSHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4794108-A | BACTERICIDES, MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0135194-A1 | Azetidinones and their production | Takeda Chemical Industries, Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |
| US-RE30752-E | CHEMICAL REACTANT FOR PROTECTING AMINO OR IMINO GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | disclosed |
| US-4010178-A | Carbonic acid esters, and the preparation thereof and their use | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-03-01 | — | — | US | disclosed |