SCHEMBL29178508

SCHEMBL29178508

CC(C)(O)c1c(Br)cnc(F)c1F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30829298 1.00 GAA (0.30) GAA
SCHEMBL38651166 0.84 GAA (0.32) GAA
SCHEMBL29178507 0.81 HTT (0.34)
SCHEMBL1769994 0.71 CYP11B2 (0.34)
SCHEMBL30821200 0.69
SCHEMBL13990717 0.67
SCHEMBL14956230 0.67 MEN1 (0.31)
SCHEMBL18484640 0.65 CTSD (0.37)
SCHEMBL23249176 0.64 SOS1 (0.35)
SCHEMBL2063973 0.64 MEN1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777126-A Imidazopyridines as IRAK4 degradants and uses thereof 武汉人福创新药物研发中心有限公司 2024-03-29 CN disclosed