SCHEMBL2917951

SCHEMBL2917951

C[Si](C)(C)C(C(=O)O)C(C(=O)O)[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
SLC7A5 Q01650 1/20 0.32
TDP1 Q9NUW8 3/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ABCB11 O95342 1/20 0.32
F2 P00734 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2C19 P33261 1/20 0.32
DUSP3 P51452 1/20 0.32
PTPN5 P54829 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958018 0.78 ALDH1A1 (0.39) ALDH1A1LMNATSHRTDP1HPGD
SCHEMBL31415558 0.71 TP53 (0.39) TP53ALDH1A1LMNATSHRTHRB
SCHEMBL5050650 0.71 TP53 (0.39) TP53ALDH1A1LMNATSHRTHRB
SCHEMBL9231359 0.69 ALDH1A1 (0.33) TP53ALDH1A1TSHRMAPT
SCHEMBL31177890 0.69
SCHEMBL451424 0.69
SCHEMBL15921098 0.67 TP53 (0.42) TP53ALDH1A1LMNATSHRSLC7A5
SCHEMBL30278577 0.67
SCHEMBL7205478 0.67
SCHEMBL15067177 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397657-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2024-06-12 EP claimed
EP-4715381-A1 METHOD FOR EVALUATING ONSET RISK OF NON-ALCOHOLIC FATTY LIVER DISEASE, AND BIOMARKERS SHIMADZU CORPORATION (JP) 2026-03-25 EP disclosed
EP-4715384-A1 METHOD FOR IDENTIFYING NON-ALCOHOLIC FATTY LIVER DISEASE, AND BIOMARKER SHIMADZU CORPORATION (JP) 2026-03-25 EP disclosed
US-20260015443-A1 POLYPROPLYENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-15 US disclosed
WO-2024237259-A1 METHOD FOR EVALUATING ONSET RISK OF NON-ALCOHOLIC FATTY LIVER DISEASE, AND BIOMARKERS 株式会社島津製作所 2024-11-21 WO disclosed
WO-2024237258-A1 METHOD FOR IDENTIFYING NON-ALCOHOLIC FATTY LIVER DISEASE, AND BIOMARKER 株式会社島津製作所 2024-11-21 WO disclosed
WO-2024025741-A1 POLYPROPYLENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-02-01 WO disclosed
EP-4107196-A1 PROPYLENE-BASED POLYMER COMPOSITIONS HAVING A HIGH MOLECULAR WEIGHT TAIL ExxonMobil Chemical Patents Inc. (US) 2022-12-28 EP disclosed
WO-2022078492-A1 MAGNESIUM-BASED SOLID AND CATALYST COMPONENT HAVING MULTIMODAL PORE DISTRIBUTION, AND PREPARATION METHODS THEREFOR 中国石油化工股份有限公司 2022-04-21 WO disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
CN-104479055-B A kind of dialkoxy-magnesium support type ingredient of solid catalyst and catalyst 任丘市利和科技发展有限公司 2017-06-06 CN disclosed
EP-2201049-B1 PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-05-31 EP disclosed
CN-104302678-A Process for the preparation of heterophasic propylene polymer compositions BASELL POLIOLEFINE ITALIA SPA 2015-01-21 CN disclosed
CN-102264527-B Pressure pipes and polyolefin composition for the manufacture thereof BASELL POLIOLEFINE SRL 2014-06-25 CN disclosed
EP-2225288-A1 SELF-LIMITING CATALYST COMPOSITION WITH BIDENTATE INTERNAL DONOR Dow Global Technologies Inc. (US) 2010-09-08 EP disclosed
EP-2201049-A2 PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS Basell Poliolefine Italia S.r.l. (IT) 2010-06-30 EP disclosed
WO-2009085649-A1 SELF-LIMITING CATALYST COMPOSITION WITH BIDENTATE INTERNAL DONOR DOW GLOBAL TECHNOLOGIES INC. (US) 2009-07-09 WO disclosed
WO-2009050045-A2 PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2009-04-23 WO disclosed
EP-1539838-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-06-15 EP disclosed
WO-2004024785-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015443-A1 POLYPROPLYENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING THE SAME PFN1, PSD, FDFT1 TP53 4433/4885ALDH1A1 3138/4885LMNA 1185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.