Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 16/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23783381 | 0.95 | DDB1 (0.64) | DDB1CRBNMEN1KMT2AF13A1 | |
| SCHEMBL30207444 | 0.95 | DDB1 (0.64) | DDB1CRBNMEN1KMT2AF13A1 | |
| SCHEMBL27225136 | 0.90 | DDB1 (0.69) | DDB1CRBN | |
| SCHEMBL26329799 | 0.90 | DDB1 (0.68) | DDB1CRBNF13A1TGM2TGM1 | |
| SCHEMBL29535454 | 0.90 | DDB1 (0.68) | DDB1CRBNF13A1TGM2TGM1 | |
| SCHEMBL25027239 | 0.90 | DDB1 (0.68) | DDB1CRBNF13A1TGM2TGM1 | |
| SCHEMBL26329796 | 0.90 | DDB1 (0.68) | DDB1CRBNF13A1TGM2TGM1 | |
| SCHEMBL25229938 | 0.89 | DDB1 (0.62) | DDB1CRBNMEN1KMT2ANPC1 | |
| SCHEMBL27167697 | 0.89 | DDB1 (0.62) | DDB1CRBNMEN1KMT2ANPC1 | |
| SCHEMBL25023293 | 0.88 | CRBN (0.66) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-117794936-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-03-29 | — | — | CN | disclosed |