SCHEMBL30207444

SCHEMBL30207444

CC(C)(C)OC(=O)N1CCC(C2CCN(c3ccc(NC4CCC(=O)NC4=O)cc3Cl)CC2)CC1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 10/20 0.64
▸ CRBN Q96SW2 10/20 0.64
▸ GPR119 Q8TDV5 7/20 0.47
▸ F13A1 P00488 1/20 0.44
▸ TGM2 P21980 1/20 0.44
▸ TGM1 P22735 1/20 0.44
▸ TGM3 Q08188 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23783381 1.00 DDB1 (0.64) DDB1CRBNGPR119F13A1TGM2
SCHEMBL29179837 0.95 DDB1 (0.69) DDB1CRBNF13A1TGM2TGM1
SCHEMBL23783207 0.90 DDB1 (0.63) DDB1CRBNGPR119F13A1TGM2
SCHEMBL25845569 0.89 DDB1 (0.61) DDB1CRBNGPR119
SCHEMBL27167697 0.88 DDB1 (0.62) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL25229938 0.88 DDB1 (0.62) DDB1CRBNMEN1KMT2ANPC1
SCHEMBL29554651 0.87 DDB1 (0.68) DDB1CRBNGPR119ALDH1A1
SCHEMBL27225136 0.86 DDB1 (0.69) DDB1CRBN
SCHEMBL25027239 0.85 DDB1 (0.68) DDB1CRBNF13A1TGM2TGM1
SCHEMBL29535454 0.85 DDB1 (0.68) DDB1CRBNF13A1TGM2TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823124-A Compounds for targeted degradation of BRD9 C4医药公司 2025-04-15 — — CN disclosed
CN-115279370-B Compounds for targeted degradation of BRD9 C4医药公司 2025-01-10 — — CN disclosed
EP-4114392-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2023-01-11 — — EP disclosed
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