Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29179947 | 0.87 | DDB1 (0.47) | CRBNDDB1 | |
| SCHEMBL29179889 | 0.82 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL30136056 | 0.80 | DDB1 (0.41) | CRBNDDB1 | |
| SCHEMBL31333703 | 0.80 | DDB1 (0.47) | CRBNDDB1 | |
| SCHEMBL31334758 | 0.80 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL31333201 | 0.80 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL31333583 | 0.79 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL31639501 | 0.78 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL31333389 | 0.78 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL29179902 | 0.78 | DDB1 (0.49) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794936-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-03-29 | — | — | CN | disclosed |