SCHEMBL31334758

SCHEMBL31334758

O=C1CCC(Nc2ccc(N3CCC(CN4CCC(C(=O)O)CC4)CC3)c(F)c2)C(=O)N1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.44
DDB1 Q16531 18/20 0.44
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333759 0.93 CRBN (0.47) CRBNDDB1
SCHEMBL31334104 0.92 CRBN (0.43) CRBNDDB1
SCHEMBL25175457 0.92 DDB1 (0.52) CRBNDDB1
SCHEMBL31333201 0.91 CRBN (0.44) CRBNDDB1LMNA
Hydrochloric Acid SCHEMBL27178791 0.91 DDB1 (0.51) CRBNDDB1
SCHEMBL31333583 0.89 CRBN (0.46) CRBNDDB1LMNA
SCHEMBL31333707 0.88 CRBN (0.47) CRBNDDB1LMNA
SCHEMBL31333703 0.88 DDB1 (0.47) CRBNDDB1
SCHEMBL30905890 0.87 DDB1 (0.54) CRBNDDB1
SCHEMBL31447643 0.87 DDB1 (0.54) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed