Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 7/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740284 | 1.00 | PDE8B (0.33) | PDE8BADORA3KDM4CNPC1RAB9A | |
| SCHEMBL19715646 | 0.89 | PDE8B (0.32) | PDE8B | |
| SCHEMBL30740321 | 0.89 | GRIN1 (0.32) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL27157558 | 0.89 | SLCO1B1 (0.33) | PDE8BADORA3KDM4CNPC1RAB9A | |
| SCHEMBL29922208 | 0.89 | SLCO1B1 (0.33) | PDE8BADORA3KDM4CNPC1RAB9A | |
| SCHEMBL29180468 | 0.89 | GRIN1 (0.32) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL30821872 | 0.82 | ABCC3 (0.33) | — | |
| SCHEMBL21057886 | 0.79 | KDM4C (0.32) | KDM4CNPC1RAB9A | |
| SCHEMBL19715663 | 0.79 | MIF (0.31) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL25230630 | 0.78 | KDM4C (0.31) | KDM4CNPC1RAB9ATGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447450-A | Triazole compounds and their use as LPAR1 antagonists | 武汉人福创新药物研发中心有限公司 | 2024-01-26 | — | — | CN | disclosed |