Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180468 | 1.00 | GRIN1 (0.32) | GRIN1GRIN2BKDM4CNPC1RAB9A | |
| SCHEMBL30740284 | 0.89 | PDE8B (0.33) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL29180491 | 0.89 | PDE8B (0.33) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL19715601 | 0.88 | SLCO1B1 (0.36) | GRIN1GRIN2BKDM4CNPC1RAB9A | |
| SCHEMBL19715646 | 0.85 | PDE8B (0.32) | — | |
| SCHEMBL21057886 | 0.81 | KDM4C (0.32) | KDM4CNPC1RAB9A | |
| SCHEMBL25230630 | 0.79 | KDM4C (0.31) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL24982985 | 0.78 | SLCO1B1 (0.39) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL29922208 | 0.77 | SLCO1B1 (0.33) | KDM4CNPC1RAB9ATGFBR1TGFBR2 | |
| SCHEMBL27157558 | 0.77 | SLCO1B1 (0.33) | KDM4CNPC1RAB9ATGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022314-A1 | TRIAZOLE COMPOUNDS AND USE THEREOF AS LPAR1 ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-02-01 | — | — | WO | disclosed |
| CN-117447450-A | Triazole compounds and their use as LPAR1 antagonists | 武汉人福创新药物研发中心有限公司 | 2024-01-26 | — | — | CN | disclosed |