Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181102 | 0.89 | TGM2 (0.69) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL571878 | 0.84 | TGM2 (0.68) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL17076474 | 0.84 | TGM2 (0.68) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL27571758 | 0.82 | KMT2A (0.71) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL18711519 | 0.82 | KMT2A (0.71) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL18883345 | 0.81 | TGM2 (0.75) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL29437927 | 0.81 | KMT2A (0.88) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL25531 | 0.81 | KMT2A (0.88) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL18702174 | 0.80 | KMT2A (0.68) | TGM2KMT2AATMEPHX1EPHX2 | |
| SCHEMBL17076473 | 0.80 | TGM2 (1.00) | TGM2KMT2AATMEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800987-A | Cephalosporin compound and application thereof in preparation of antibacterial drugs | 复旦大学 | 2024-04-02 | — | — | CN | claimed |
| CN-117800987-A | Cephalosporin compound and application thereof in preparation of antibacterial drugs | 复旦大学 | 2024-04-02 | — | — | CN | disclosed |