Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27420222 | 0.87 | KDM4E (0.44) | KDM4EHPGDALDH1A1MAPTTSHR | |
| SCHEMBL30731126 | 0.84 | KDM4E (0.42) | KDM4EHPGDALDH1A1MAPTTSHR | |
| SCHEMBL28483122 | 0.84 | KDM4E (0.42) | KDM4EHPGDALDH1A1MAPTTSHR | |
| SCHEMBL28563434 | 0.81 | KDM4E (0.42) | KDM4EHPGDALDH1A1MAPTTSHR | |
| SCHEMBL31362806 | 0.77 | GAA (0.47) | KDM4EHPGDMAPTTSHRHTT | |
| Phenol SCHEMBL27348628 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTCA1RAB9A | |
| Phenol SCHEMBL28162156 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTRAB9AKMT2A | |
| Phenol SCHEMBL28342610 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTCA1RAB9A | |
| Phenol SCHEMBL2640784 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTRAB9AKMT2A | |
| Phenol SCHEMBL1847412 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117487811-A | Compositions and methods for treating complications and diseases associated with von willebrand factor | 邦德治疗有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-110520128-B | Compositions and methods for treating complications and diseases associated with von Willebrand Factor | 邦德治疗有限公司 | 2023-11-14 | — | — | CN | disclosed |