Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 5/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL2640784 | 1.00 | ALDH1A1 (0.40) | ALDH1A1RAB9AMEN1KMT2AACE | |
| Phenol SCHEMBL28162156 | 1.00 | ALDH1A1 (0.40) | ALDH1A1RAB9AMEN1KMT2AACE | |
| Phenol SCHEMBL27348628 | 0.91 | ALDH1A1 (0.46) | ALDH1A1RAB9AMEN1KMT2AITGB2 | |
| Phenol SCHEMBL28342610 | 0.91 | ALDH1A1 (0.46) | ALDH1A1RAB9AMEN1KMT2AITGB2 | |
| Benzene SCHEMBL28092853 | 0.88 | ECE1 (0.39) | ALDH1A1RAB9AMEN1KMT2AITGB2 | |
| Phenol SCHEMBL170523 | 0.83 | ALDH1A1 (0.39) | ALDH1A1RAB9AMEN1KMT2AHPGDS | |
| Phenol SCHEMBL29254468 | 0.83 | ALDH1A1 (0.39) | ALDH1A1RAB9AMEN1KMT2AHPGDS | |
| SCHEMBL3856802 | 0.83 | ECE1 (0.42) | ITGB2ICAM1ITGAL | |
| SCHEMBL7034111 | 0.83 | ECE1 (0.42) | ITGB2ICAM1ITGAL | |
| SCHEMBL29181774 | 0.76 | KDM4E (0.43) | ALDH1A1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506129-A | Kit for identifying malignant tumor and application thereof | AGENCY SCIENCE TECH & RES | 2019-11-26 | — | — | CN | disclosed |
| CN-105263927-B | Inhibitors of glutaminyl cyclase | 前体生物药物股份公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-108218849-A | New inhibitor | 前体生物药物股份公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-106061974-B | Maleimide derivatives as the conditioning agent of WNT approach | 新加坡科技研究局 | 2018-04-20 | — | — | CN | disclosed |
| CN-106061974-A | Maleimide derivatives as modulators of WNT pathway | 新加坡科技研究局 | 2016-10-26 | — | — | CN | disclosed |
| CN-102186475-B | novel inhibitors | 前体生物药物股份公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-105263927-A | Novel inhibitors | PROBILDRUG AG | 2016-01-20 | — | — | CN | disclosed |
| CN-105246889-A | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES LLC | 2016-01-13 | — | — | CN | disclosed |
| CN-102791704-B | The heterocycle inhibitor of glutaminyl cyclase (QC, EC 2.3.2.5) | PROBIODRUG AG (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-104853758-A | Treatment of pulmonary disease | INTERCEPT PHARMACEUTICALS INC | 2015-08-19 | — | — | CN | disclosed |
| EP-1040111-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-2000006169-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-1999030713-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999031099-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0885205-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| CN-1202893-A | Novel isoxazoline and isoxazole fibrinogen receptor antagonists | DU PONT MERCK PHARMA (US) | 1998-12-23 | — | — | CN | disclosed |
| WO-1997031910-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-09-04 | — | — | WO | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |