Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288576 | 0.80 | ALPG (0.42) | ALPGPLAAALPLALDH1A1KDM4E | |
| SCHEMBL1165647 | 0.80 | ALPG (0.42) | ALPGPLAAALPLALDH1A1KDM4E | |
| SCHEMBL29182103 | 0.78 | ALDH1A1 (0.36) | ALPGPLAAALPLALDH1A1KDM4E | |
| SCHEMBL28746087 | 0.78 | ALPG (0.41) | ALPGPLAAALPLALDH1A1KDM4E | |
| SCHEMBL1353073 | 0.78 | ALPG (0.41) | ALPGPLAAALPLALDH1A1KDM4E | |
| SCHEMBL17067661 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| Ethane SCHEMBL27625282 | 0.77 | ALPG (0.40) | ALPGPLAAALPLALDH1A1KDM4E | |
| SCHEMBL28151261 | 0.77 | ALPG (0.40) | ALPGPLAAALPLALDH1A1KDM4E | |
| SCHEMBL19201556 | 0.75 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL11646580 | 0.74 | ALPG (0.35) | ALPGPLAAALPLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551035-A | Nitrogen-containing trisubstituted olefin compound and preparation method and application thereof | 华南师范大学 | 2024-02-13 | — | — | CN | disclosed |