Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.54 |
| ▸ | AXL | P30530 | 7/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.51 |
| ▸ | KIT | P10721 | 3/20 | 0.51 |
| ▸ | FLT3 | P36888 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | MST1R | Q04912 | 2/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | STK25 | O00506 | 1/20 | 0.48 |
| ▸ | CIT | O14578 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678364 | 0.85 | MET (0.55) | METAXLKDRPDGFRBKIT | |
| SCHEMBL3911157 | 0.80 | MET (0.51) | METAXLKDRKITFLT3 | |
| Hydrochloric Acid SCHEMBL15917934 | 0.78 | MET (0.56) | METAXLKDRPDGFRBKIT | |
| Hydrochloric Acid SCHEMBL15917992 | 0.78 | MET (0.56) | METAXLKDRPDGFRBKIT | |
| Hydrochloric Acid SCHEMBL15918148 | 0.78 | MET (0.56) | METAXLKDRPDGFRBKIT | |
| SCHEMBL28676846 | 0.78 | MET (0.57) | METAXLKDRPDGFRBKIT | |
| SCHEMBL28686931 | 0.77 | HDAC2 (0.57) | METAXLKDRPDGFRBKIT | |
| SCHEMBL372084 | 0.77 | MET (0.53) | METAXLKDRPDGFRBKIT | |
| SCHEMBL372182 | 0.77 | MET (0.53) | METAXLKDRPDGFRBKIT | |
| SCHEMBL372228 | 0.77 | MET (0.52) | METAXLKDRPDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924288-B | Quinolinyl-containing compound, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2024-04-05 | — | — | CN | disclosed |