Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.47 |
| ▸ | ESR1 | P03372 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850122 | 0.75 | ESR1 (0.40) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL4450591 | 0.75 | ESR2 (0.74) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL15717660 | 0.73 | ESR2 (0.71) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL12336908 | 0.73 | ESR2 (0.78) | ESR2ESR1MEN1KMT2ALMNA | |
| SCHEMBL28978818 | 0.72 | ESR2 (0.43) | ESR2ESR1MEN1KMT2AGAA | |
| SCHEMBL28267335 | 0.71 | ESR1 (0.55) | ESR2ESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL19783218 | 0.71 | GRM5 (0.46) | ESR2ESR1MEN1KMT2AGAA | |
| SCHEMBL19782299 | 0.71 | ESR1 (0.42) | ESR2ESR1MEN1KMT2AGAA | |
| SCHEMBL28183497 | 0.69 | ESR2 (0.44) | ESR2ESR1MEN1KMT2AGAA | |
| SCHEMBL15275550 | 0.68 | ESR2 (0.83) | ESR2ESR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794920-A | N- (hydroxyalkyl (hetero) aryl) tetrahydrofurancarboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-03-29 | — | — | CN | disclosed |