Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | TET3 | O43151 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4B | O94953 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182995 | 0.75 | ESR2 (0.47) | ESR1ESR2KMT2ASMN1; SMN2GFER | |
| SCHEMBL29112221 | 0.73 | ESR1 (0.46) | ESR1ESR2KMT2ASMN1; SMN2GFER | |
| SCHEMBL4450591 | 0.68 | ESR2 (0.74) | ESR1ESR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6547521 | 0.67 | ESR1 (0.68) | ESR1ESR2KMT2ASMN1; SMN2GFER | |
| SCHEMBL25204480 | 0.67 | ALDH1A1 (0.43) | ESR1ESR2SMN1; SMN2NPFFR1NPFFR2 | |
| SCHEMBL29818274 | 0.67 | ALDH1A1 (0.43) | ESR1ESR2SMN1; SMN2NPFFR1NPFFR2 | |
| SCHEMBL27020067 | 0.67 | ESR1 (0.37) | ESR1ESR2KMT2ASMN1; SMN2NPFFR1 | |
| SCHEMBL27042080 | 0.67 | ESR1 (0.37) | ESR1ESR2KMT2ASMN1; SMN2GFER | |
| SCHEMBL12984299 | 0.67 | ESR1 (0.39) | ESR1ESR2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4920963 | 0.66 | ALDH1A1 (0.44) | ESR2KMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945571-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2022-08-26 | — | — | CN | disclosed |