Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.74 |
| ▸ | ESR1 | P03372 | 8/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.52 |
| ▸ | HTR3B | O95264 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12336908 | 0.97 | ESR2 (0.78) | ESR2ESR1MEN1KMT2AHTR3E | |
| SCHEMBL15717660 | 0.92 | ESR2 (0.71) | ESR2ESR1MEN1KMT2AHTR3E | |
| SCHEMBL17928347 | 0.91 | ESR2 (0.69) | ESR2ESR1MEN1KMT2AHTR3E | |
| SCHEMBL20198257 | 0.87 | ESR2 (0.66) | ESR2ESR1MEN1KMT2AHTR3E | |
| SCHEMBL25693071 | 0.87 | ESR2 (0.66) | ESR2ESR1MEN1KMT2AHTR3E | |
| SCHEMBL29022906 | 0.85 | ESR2 (1.00) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL6932651 | 0.85 | ESR2 (0.57) | ESR2ESR1MEN1KMT2AHTR3E | |
| SCHEMBL15275550 | 0.85 | ESR2 (0.83) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL12336909 | 0.85 | ESR2 (0.69) | ESR2ESR1MEN1KMT2AHTR3E | |
| SCHEMBL23466340 | 0.84 | ESR2 (0.68) | ESR2ESR1MEN1KMT2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404221-B2 | Methods of arene alkenylation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-09-02 | — | — | US | disclosed |
| EP-4588968-A1 | ALIPHATIC POLYKETONE COMPOSITION WITH IMPROVED THERMAL STABILITY | TE Connectivity Solutions GmbH (CH) | 2025-07-23 | — | — | EP | disclosed |
| US-20250230293-A1 | Aliphatic Polyketone Composition with Improved Thermal Stability | TE CONNECTIVITY SOLUTIONS GMBH (CH) | 2025-07-17 | — | — | US | disclosed |
| US-11833494-B2 | Catalysts and methods for forming alkenyl substituted arenes | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230312813-A1 | METHOD FOR PRODUCING ANION EXCHANGE RESIN AND METHOD FOR PRODUCING ELECTROLYTE MEMBRANE | UNIVERSITY OF YAMANASHI (JP) | 2023-10-05 | — | — | US | disclosed |
| US-20230312813-A1 | METHOD FOR PRODUCING ANION EXCHANGE RESIN AND METHOD FOR PRODUCING ELECTROLYTE MEMBRANE | UNIVERSITY OF YAMANASHI (JP) | 2023-10-05 | — | — | US | disclosed |
| US-11772083-B2 | Catalysts and methods for forming alkenyl and alkyl substituted arenes | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-10-03 | — | — | US | disclosed |
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | WILLIAM MARSH RICE UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-07-27 | — | — | US | disclosed |
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20090326240-A1 | Iron-Copper Co-Catalyzed Process for Carbon-Carbon or Carbon-Heteroatom Bonding | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-12-31 | — | — | US | disclosed |
| US-20090326240-A1 | Iron-Copper Co-Catalyzed Process for Carbon-Carbon or Carbon-Heteroatom Bonding | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-12-31 | — | — | US | disclosed |
| EP-2043970-A2 | IRON-COPPER CO-CATALYZED PROCESS FOR CARBON-CARBON OR CARBON-HETEROATOM BONDING | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008004088-A2 | IRON-COPPER CO-CATALYZED PROCESS FOR CARBON-CARBON OR CARBON-HETEROATOM BONDING | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008004088-A2 | IRON-COPPER CO-CATALYZED PROCESS FOR CARBON-CARBON OR CARBON-HETEROATOM BONDING | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-01-10 | — | — | WO | disclosed |
| US-20070066825-A1 | Chiral ligands and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| CN-1791607-A | Chiral ligands and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2006-06-21 | — | — | CN | disclosed |
| EP-0947561-B1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6235861-B1 | REACTION INHIBITOR IS ADDED TO THE COMPOSITION COMPRISING AN ALKENYLATED ORGANOPOLYSILOXANE, AN ORGANOHYDROGENPOLYSILOXANE, AND A PLATINUM CATALYST. | THREE BOND (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0947561-A1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066825-A1 | Chiral ligands and their transition metal complexes | PICALM, CACYBP, SLC39A14 | ESR2 637/4885ESR1 980/4885MEN1 1322/4885 |
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | CYBB, CBR3, AHR | ESR2 773/4885ESR1 179/4885MEN1 4381/4885 |
| US-11767291-B2 | Preparation of secondary amines with electrophilic N-linchpin reagents | PNMT, NCL, NPM1 | ESR2 2476/4885ESR1 1540/4885MEN1 296/4885 |
| US-20230312813-A1 | METHOD FOR PRODUCING ANION EXCHANGE RESIN AND METHOD FOR PRODUCING ELECTROLYTE MEMBRANE | SLC9A5, SLC9A1, SLC9A2 | ESR2 2133/4885ESR1 2320/4885MEN1 953/4885 |
| US-12404221-B2 | Methods of arene alkenylation | CYBB, CBR3, AHR | ESR2 773/4885ESR1 179/4885MEN1 4381/4885 |
| US-20090326240-A1 | Iron-Copper Co-Catalyzed Process for Carbon-Carbon or Carbon-Heteroatom Bonding | FECH, HCCS, SOD1 | ESR2 2107/4885ESR1 1352/4885MEN1 2165/4885 |
| US-11833494-B2 | Catalysts and methods for forming alkenyl substituted arenes | SOD1, ALKBH3, HACL2 | ESR2 1497/4885ESR1 815/4885MEN1 3479/4885 |
| US-11772083-B2 | Catalysts and methods for forming alkenyl and alkyl substituted arenes | ALKBH3, SOD1, GARS1 | ESR2 1543/4885ESR1 672/4885MEN1 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.