SCHEMBL29183121

SCHEMBL29183121

C[C@H]1CC=CCN1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.30
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30565809 1.00 TSHR (0.34) TSHRMAPTACE
SCHEMBL27390283 0.83 TSHR (0.34) TSHRMAPTACE
SCHEMBL28200411 0.76 ACE (0.34) ACE
SCHEMBL3390185 0.74 ACE (0.33) ACE
SCHEMBL28856332 0.74 ACE (0.30) ACE
SCHEMBL17336127 0.74 ACE (0.33) ACE
SCHEMBL25391662 0.74
SCHEMBL30477339 0.74 PREP (0.41) TSHR
SCHEMBL31510820 0.71
SCHEMBL3390437 0.71 POLB (0.34) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209441-A Novel amine derivatives 住友制药株式会社 2023-06-02 CN disclosed