SCHEMBL30565809

SCHEMBL30565809

CC1CC=CCN1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.30
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29183121 1.00 TSHR (0.34) TSHRMAPTACE
SCHEMBL27390283 0.83 TSHR (0.34) TSHRMAPTACE
SCHEMBL28200411 0.76 ACE (0.34) ACE
SCHEMBL3390185 0.74 ACE (0.33) ACE
SCHEMBL28856332 0.74 ACE (0.30) ACE
SCHEMBL17336127 0.74 ACE (0.33) ACE
SCHEMBL25391662 0.74
SCHEMBL30477339 0.74 PREP (0.41) TSHR
SCHEMBL31510820 0.71
SCHEMBL3390437 0.71 POLB (0.34) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025035108-A2 INHIBITORS OF PARG ARASE THERAPEUTICS INC. (US) 2025-02-13 WO disclosed
CN-117157299-A Tricyclic heterocyclic derivative, composition and application thereof 北京丹擎医药科技有限公司 2023-12-01 CN disclosed
WO-2023151069-A1 PYRROLO[2,3-D]SIX-MEMBERED HETEROAROMATIC RING DERIVATIVE, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 湖南南新制药股份有限公司 2023-08-17 WO disclosed