Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 7/20 | 0.53 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.53 |
| ▸ | STS | P08842 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21748545 | 0.84 | SSTR4 (0.76) | SSTR4SSTR1 | |
| SCHEMBL8182207 | 0.82 | ADRB2 (0.52) | SSTR4SSTR1STSALDH1A1NPC1 | |
| SCHEMBL4573880 | 0.82 | ADRB2 (0.52) | SSTR4SSTR1STSALDH1A1NPC1 | |
| SCHEMBL22265811 | 0.79 | KDM4E (0.54) | SSTR4SSTR1STSMAPTGPR119 | |
| SCHEMBL69764 | 0.78 | MAPT (0.54) | STSALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL5994005 | 0.77 | STS (0.54) | STSALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL68971 | 0.76 | KDM1A (0.56) | STSGPR119MEN1KMT2A | |
| SCHEMBL4499579 | 0.75 | RBP4 (0.53) | SSTR4SSTR1STSGPR119KDM4E | |
| SCHEMBL21774914 | 0.75 | SSTR4 (0.76) | SSTR4SSTR1 | |
| SCHEMBL29183193 | 0.75 | SSTR4 (0.76) | SSTR4SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236423-B | Piperidinyl-3- (aryloxy) propanamides and propionic acid esters | 武田药品工业株式会社 | 2024-02-06 | — | — | CN | disclosed |