SCHEMBL29183288

SCHEMBL29183288

COc1ccc(S(=O)(=O)NCCCC2CCCC2)cc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.68
PKM P14618 1/20 0.68
USP2 O75604 2/20 0.58
KMT2A Q03164 2/20 0.58
HTT P42858 1/20 0.58
SMN1; SMN2 Q16637 3/20 0.56
MEN1 O00255 1/20 0.54
HTR7 P34969 1/20 0.53
POLB P06746 1/20 0.52
CYP19A1 P11511 1/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29183284 0.99 ALDH1A1 (0.67) ALDH1A1PKMUSP2KMT2AHTT
SCHEMBL29183287 0.92 ALDH1A1 (0.63) ALDH1A1PKMUSP2KMT2AHTT
SCHEMBL6624376 0.90 USP2 (0.62) ALDH1A1PKMUSP2KMT2AHTT
SCHEMBL23648881 0.85 ALDH1A1 (0.52) ALDH1A1PKMUSP2KMT2AHTT
SCHEMBL8030757 0.83 ALDH1A1 (0.65) ALDH1A1PKMKMT2ASMN1; SMN2MEN1
SCHEMBL29183291 0.82 ALDH1A1 (0.64) ALDH1A1PKMUSP2KMT2AHTT
SCHEMBL8392223 0.81 ALDH1A1 (0.62) ALDH1A1PKMKMT2ASMN1; SMN2HTR7
SCHEMBL6623889 0.80 ALDH1A1 (0.60) ALDH1A1PKMKMT2ASMN1; SMN2HTR7
SCHEMBL8392017 0.80 ALDH1A1 (0.60) ALDH1A1PKMKMT2ASMN1; SMN2HTR7
SCHEMBL5563528 0.79 ALDH1A1 (0.86) ALDH1A1PKMUSP2KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658945-A Synthesis method of persulfate-induced alkylation modified nitrogen heterocyclic compound 浙江工业大学 2024-03-08 CN disclosed
CN-117645581-A Method for synthesizing series of functional groups of photocatalytic inert C (sp 3) -H bond 浙江工业大学台州研究院 2024-03-05 CN disclosed