SCHEMBL29183294

SCHEMBL29183294

COc1ccc(S(=O)(=O)NCCCCC(C)C)cc1

nearest known ligand 0.79

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.79
PKM P14618 1/20 0.79
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
USP2 O75604 1/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
POLB P06746 1/20 0.56
HTR7 P34969 1/20 0.53
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20730795 0.95 ALDH1A1 (0.77) ALDH1A1PKMKMT2AMEN1USP2
SCHEMBL1465523 0.83 ALDH1A1 (0.87) ALDH1A1PKMKMT2AMEN1USP2
SCHEMBL13251389 0.83 ALDH1A1 (0.64) ALDH1A1PKMKMT2AMEN1
SCHEMBL5563528 0.82 ALDH1A1 (0.86) ALDH1A1PKMKMT2AMEN1USP2
SCHEMBL19362573 0.82 ALDH1A1 (0.62) ALDH1A1PKMKMT2AMEN1SMN1; SMN2
SCHEMBL5741229 0.82 ALDH1A1 (0.62) ALDH1A1PKMKMT2AMEN1SMN1; SMN2
SCHEMBL7392549 0.82 ALDH1A1 (0.84) ALDH1A1PKMKMT2AMEN1USP2
SCHEMBL9149721 0.82 ALDH1A1 (0.84) ALDH1A1PKMKMT2AMEN1USP2
SCHEMBL29163150 0.82 ALDH1A1 (0.84) ALDH1A1PKMKMT2AMEN1USP2
SCHEMBL29183282 0.82 ALDH1A1 (0.84) ALDH1A1PKMKMT2AMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658945-A Synthesis method of persulfate-induced alkylation modified nitrogen heterocyclic compound 浙江工业大学 2024-03-08 CN disclosed