Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | CASP2 | P42575 | 2/20 | 0.43 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5980593 | 0.80 | S1PR2 (0.53) | BLMDRD3TSHRANPEP | |
| Amifostine SCHEMBL4709602 | 0.77 | BLM (1.00) | BLMDRD3CA12CA2CA4 | |
| Amifostine SCHEMBL18464 | 0.77 | BLM (1.00) | BLMDRD3CA12CA2CA4 | |
| Spermine SCHEMBL867750 | 0.76 | CA12 (0.56) | BLMDRD3CA12CA2CA4 | |
| Amifostine SCHEMBL1231172 | 0.76 | BLM (0.96) | BLMDRD3CA12CA2CA4 | |
| Amifostine SCHEMBL4732534 | 0.76 | BLM (0.96) | BLMDRD3CA12CA2CA4 | |
| Amifostine SCHEMBL4383022 | 0.76 | BLM (0.96) | BLMDRD3CA12CA2CA4 | |
| Amifostine SCHEMBL317195 | 0.76 | BLM (0.96) | BLMDRD3CA12CA2CA4 | |
| Amifostine SCHEMBL4562808 | 0.76 | BLM (0.96) | BLMDRD3CA12CA2CA4 | |
| Amifostine SCHEMBL5309668 | 0.76 | BLM (0.96) | BLMDRD3CA12CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117815189-A | Preparation method for industrially preparing amifostine freeze-dried preparation | 四川汇宇制药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |