Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864485 | 0.84 | EPHX2 (0.59) | EPHX2NR1H4PPARAPPARGHTR2C | |
| SCHEMBL6635990 | 0.80 | EPHX2 (0.61) | EPHX2NR1H4PPARAPPARGHTR2C | |
| SCHEMBL3966634 | 0.78 | EPHX2 (0.63) | EPHX2NR1H4PPARAPPARGHTR2C | |
| SCHEMBL6665002 | 0.78 | EPHX2 (0.59) | EPHX2NR1H4PPARAPPARGHTR2C | |
| SCHEMBL27859550 | 0.77 | EPHX2 (0.62) | EPHX2NR1H4PPARAPPARGHTR2C | |
| SCHEMBL4575587 | 0.76 | GAA (0.65) | EPHX2NR1H4SMN1; SMN2 | |
| SCHEMBL28975453 | 0.76 | MMP8 (0.58) | CA12CA1CA2CA7 | |
| SCHEMBL23564738 | 0.76 | EPHX2 (0.57) | EPHX2NR1H4PPARAPPARGHTR2C | |
| SCHEMBL4575470 | 0.76 | EPHX2 (0.57) | EPHX2NR1H4PPARAPPARGHTR2C | |
| SCHEMBL31248368 | 0.76 | EPHX2 (0.57) | EPHX2NR1H4PPARAPPARGHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896685-B | Indoleamine-2, 3-dioxygenase (IDO) inhibitors | 益方生物科技(上海)股份有限公司 | 2024-02-06 | — | — | CN | disclosed |