Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 10/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.74 |
| ▸ | PGR | P06401 | 1/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
| ▸ | BLVRB | P30043 | 1/20 | 0.74 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.74 |
| ▸ | PPID | Q08752 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30804874 | 1.00 | XDH (0.74) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30804875 | 0.95 | XDH (0.73) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29183566 | 0.95 | XDH (0.73) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30253977 | 0.91 | XDH (0.76) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL27895928 | 0.91 | XDH (0.76) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL8866996 | 0.90 | XDH (0.72) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29460288 | 0.90 | XDH (0.74) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30804888 | 0.89 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29183639 | 0.89 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523341 | 0.88 | XDH (0.79) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777050-A | Febuxostat 4-position ether derivative and pharmaceutical composition, preparation method and application thereof | 广西师范大学 | 2024-03-29 | — | — | CN | disclosed |