Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | BLVRB | P30043 | 1/20 | 0.60 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30804888 | 1.00 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30804881 | 0.95 | XDH (0.59) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29183565 | 0.95 | XDH (0.59) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523342 | 0.91 | XDH (0.65) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30804874 | 0.89 | XDH (0.74) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29183564 | 0.89 | XDH (0.74) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523349 | 0.89 | XDH (0.60) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL31601 | 0.86 | XDH (0.80) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29655618 | 0.86 | XDH (0.80) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL459545 | 0.85 | XDH (0.59) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777050-A | Febuxostat 4-position ether derivative and pharmaceutical composition, preparation method and application thereof | 广西师范大学 | 2024-03-29 | — | — | CN | disclosed |