Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 7/20 | 0.59 |
| ▸ | RXRB | P28702 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14536502 | 0.88 | MEN1 (0.73) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL254794 | 0.85 | NR4A2 (0.72) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL254715 | 0.85 | NR4A2 (0.72) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL18687040 | 0.84 | MEN1 (0.74) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8134318 | 0.82 | NR4A2 (0.85) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL12637239 | 0.81 | MEN1 (0.65) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL31141980 | 0.80 | MEN1 (0.79) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL1750167 | 0.79 | NR4A2 (0.86) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL14190789 | 0.78 | RXRA (0.60) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL14511354 | 0.76 | NR4A2 (0.59) | NR4A2NR4A1NR4A3RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041228-B | Synthesis method of bumetanide | 沈阳希贝康医药科技有限公司 | 2024-03-12 | — | — | CN | claimed |